Simple estimate of creatinine clearance from plasma creatinine in neonates.

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Simple estimate of creatinine clearance from plasma creatinine in neonates.

Thirteen newborn infants, 8 preterm and 5 term, with either mild or serious neonatal asphyxia were studied. From the first 24 hours of life to day 13, glomerular filtration rate (GFR) estimated by creatinine clearance was compared with the values obtained using Schwartz's formula: GFR (ml/min per 1.73 m2) = 0.55 x length (cm)/plasma creatinine (mg/100 ml). Both in term and preterm infants, valu...

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Calculation of creatinine clearance from plasma creatinine.

Glomerular filtration rate (GFR) is commonly assessed by measurement of endogenous creatinine clearance (Ccr). Several formulae have been described to calculate Ccr from plasma creatinine. I have evaluated the effectiveness of four formulae in 35 healthy subjects (21M and 14F, 18-34 years) and in 41 patients (24M, 17F, 20-69 years) attending a renal clinic with diminished renal function (serum ...

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Retooling the creatinine clearance equation to estimate kinetic GFR when the plasma creatinine is changing acutely.

It is often desirable to estimate the GFR (eGFR) at the bedside to assess AKI or renal recovery. Current eGFR equations estimate kidney function when the plasma creatinine is stable, but do not work if the plasma creatinine is changing rapidly. To analyze kidney function in the acute setting, a simple formula is proposed that requires only a modest number of inputs that are readily obtainable f...

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The assessment of glomerular function: creatinine clearance or plasma creatinine?

Plasma creatinine concentration is superior to creatinine clearance for the detection of abnormal glomerular function, of changes of glomerular function in patients with chronic renal disease. Creatinine clearance should be abandoned as the routine assessment of glomerular function.

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Plasma chromogen and the endogenous creatinine clearance.

One of the troubles of using the endogenous creatinine clearance to measure the filtration rate is that plasma and serum contain chromogens, other than creatinine, which give a colour with the Jaffe reaction. The creatinine can, however, be isolated by adsorption on Fuller's earth (Gaebler and Keltch, 1928) and subsequently eluted with the alkaline picrate used for colour production (Borsook, 1...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1982

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.57.4.297